† Without and with adjustment for BMI. Simple adjusted includes covariates for registry site (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), with and without BMI (18.5 – <25, 25 – <30, ?30kg/m 2 ).
‡ Fully adjusted model includes covariates for registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), BMI (18.5 – <25, 25 – <30, ?30kg/m 2 ), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded.
§ P worth out of Wald fact to test to own an overall total perception from categorical BI-RADS density. All of the statistical assessment had been one or two-sided.
Whether or not BI-RADS occurrence didn’t tailor likelihood of cancer of the breast demise in the relationship to most other pathological items, ladies having BI-RADS step 1 thickness tended to feel the highest exposure, in any stratum
¶ AJCC stage is roofed as the a good categorical covariate inside patterns having all the grade joint, having and you can in the place of stage IV.
Emergency model outcomes for brand new family members between mammographic occurrence and you can exposure away from breast cancer dying, full and also by AJCC stage*
* AJCC = American Mutual Committee on Cancer tumors; BI-RADS = Nipple Imaging Revealing and you may Research Program; Body mass index = body mass index; CI = rely on period; Hour = threat ratio. N = 96 female excluded regarding the end in-particular models.
† Without and with adjustment for BMI. Simple adjusted includes covariates for registry site (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), with and without BMI (18.5 – <25, 25 – <30, ?30kg/m 2 ).
‡ Fully adjusted model includes covariates for registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), BMI (18.5 – <25, 25 – <30, ?30kg/m 2 ), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded.
§ P value from Wald figure to test to own a complete perception of categorical BI-RADS density. All analytical screening was basically two-sided.
Even when BI-RADS occurrence don’t modify threat of breast cancer demise for the relationship to other pathological situations, women which have BI-RADS step 1 occurrence tended to feel the high risk, in just about any stratum
¶ AJCC stage is roofed since a good categorical covariate in the models with all of the amount mutual, having and without stage IV.
One of people which have cancers of at least dos.0cm, BI-RADS 1 thickness was in the an increased threat of nipple cancer tumors demise (Hours = step 1.55, 95% CI = step one.14 so you’re able kupony dabble to 2.09; P = .003 to own overall effectation of BI-RADS thickness; Table 4). Women who got one another BI-RADS 1 occurrence and you will large-levels cancers had a heightened risk of breast cancer passing (Time = 1.forty-five, 95% CI = step 1.05 to help you dos.02; P = .thirteen to own overall effectation of density).
Emergency design results for the latest family between mammographic density and you can risk off cancer of the breast dying, stratified by the tumor services, AJCC amounts We–IV mutual*
* N = 96 women excluded from cause-specific models. Fully adjusted model includes covariates for AJCC stage (I, IIA, IIB, III, IV), registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), body mass index (18.5 – <25, 25 – <30, ?30kg/m 2 ), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded. AJCC = American Joint Committee on Cancer; BI-RADS = Breast Imaging Reporting and Data System; CI = confidence interval; ER = estrogen receptor; HR = hazard ratio; PR = progesterone receptor.
